| 摘要 |
Disclosed are a beta -carboline derivative represented by the formula: <CHEM> wherein R<1> represents hydrogen atom, a lower alkyl group, a lower alkoxy group or hydroxy group; R<5> represents hydrogen atom, or R<1> and R<5> are bonded to represent a lower alkylenedioxy group; R<2> represents hydrogen atom, a halogen atom, a lower alkoxy group or hydroxy group; R<3> represents hydrogen atom, a carbamoyl lower alkyl group, a lower alkyl group, a carboxy lower alkyl group or a lower alkoxycarbonyl lower alkyl group; R<4> represents hydrogen atom, a lower alkyl group, a carboxy lower alkyl group, a lower alkoxycarbonyl lower alkyl group, a lower alkanoyl group, an arylcarbonyl group, a lower alkanesulfonyl group, a lower alkoxycarbonyl group, an aralkyl group, formyl group or a di(lower alkyl)sulfamoyl group; n represents 0, 1 or 2; and the symbol * represents an asymmetric carbon atom, or a pharmaceutically acceptable salt thereof, and a process for preparing the same. |
