发明名称 |
Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof |
摘要 |
New proteins, termed GAP 31, obtainable from the seeds of Gelonium multiflorum, and DAP 30 and DAP 32, obtainable from the leaves or seeds of Dianthus caryophyllus, or the above proteins produced by recombinant means, are useful for treating HIV infections. In treating HIV infections, the protein is administered alone or in conjunction with other anti-HIV therapeutics. Also provided are processes for purifying the proteins, DNA sequences encoding the proteins, hosts expressing the proteins, recombinant DNA methods for expressing the proteins, and antibodies specific for the proteins.
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申请公布号 |
US5317009(A) |
申请公布日期 |
1994.05.31 |
申请号 |
US19910749541 |
申请日期 |
1991.08.26 |
申请人 |
NEW YORK UNIVERSITY;AMERICAN BIOSCIENCES, INC.;NATIONAL INSTITUTES OF HEALTH |
发明人 |
LEE-HUANG, SYLVIA;KUNG, HSIANG-FU;HUANG, PAUL L.;HUANG, PHILIP L.;HUANG, PETER;HUANG, HENRY I.;CHEN, HAO-CHIA |
分类号 |
A61K38/00;A61K39/395;A61K47/48;A61P31/12;A61P31/18;C07K1/18;C07K1/22;C07K1/30;C07K14/415;C07K16/00;C07K16/16;C12N15/09;C12P21/02;(IPC1-7):C07K13/00;C07K15/10;C07K15/14 |
主分类号 |
A61K38/00 |
代理机构 |
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