发明名称 |
Monoclonal antibodies capable of recognizing n-acetylneuraminic acid in beta-arrangement used for diagnosis and prognosis of tumors and acute inflammatory diseases |
摘要 |
A hybridoma producing a monoclonal antibody specific to N-acetylneuraminic acid or a derivative thereof in the beta-arrangement as an epitope or antigenic determinant is herein disclosed. The monoclonal antibody produced by the hybridoma can be used in clinical purposes such as diagnosis and/or prognosis of a certain kinds of cancers and acute inflammatory diseases. The hybridoma can be generated by fusing (i) B cells or lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a derivative thereof in beta-arrangement as an antigen and (ii) myeloma cells. |
申请公布号 |
IL88322(A) |
申请公布日期 |
1994.05.30 |
申请号 |
IL19880088322 |
申请日期 |
1988.11.08 |
申请人 |
MECT CORPORATION |
发明人 |
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分类号 |
G01N33/53;A61K38/00;A61K39/395;C07K16/18;C07K16/30;C12N5/18;C12N5/20;C12P21/08;C12R1/91;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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