FLUIDIZED INTESTINAL SUBMUCOSA AND ITS USE AS AN INJECTABLE TISSUE GRAFT

摘要

2149324 9411008 PCTABS00032 A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa and basilar portions of the tunica mucosa of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.