| 发明名称 |
QUINUCLIDINE DERIVATIVE AS SUBSTANCE P ANTAGONIST |
| 摘要 |
This invention relates to the quinuclidine derivative (2S, 3S)-N-(5-n-propyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine and its pharmaceutically acceptable salts. These compounds are substance P antagonists and are useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain. |
| 申请公布号 |
WO9411368(A1) |
申请公布日期 |
1994.05.26 |
| 申请号 |
WO1993US06624 |
申请日期 |
1993.07.19 |
| 申请人 |
PFIZER INC.;ITO, FUMITAKA;KONDO, HIROSHI;NAKANE, MASAMI;SHIMADA, KAORU |
发明人 |
ITO, FUMITAKA;KONDO, HIROSHI;NAKANE, MASAMI;SHIMADA, KAORU |
| 分类号 |
A61K31/435;A61P1/00;A61P9/08;A61P9/12;A61P11/00;A61P17/00;A61P25/00;A61P25/02;A61P25/04;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P25/28;A61P25/30;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07D453/02;(IPC1-7):C07D453/02 |
主分类号 |
A61K31/435 |
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