| 发明名称 |
PERIPHERALIZATION OF HEMATOPOIETIC STEM CELLS |
| 摘要 |
The invention provides methods for peripheralizing CD34<+> cells, including hematopoietic stem cells. In a first aspect, the method comprises the step of administering a blocking agent of VLA-4 antigen on the surface of CD34<+> cells. In a second aspect, the method comprises administering a blocking agent of VLA-4 antigen on the surface of CD34<+> cells and administering a stimulating agent of CD34<+> cell proliferation in vivo. The method according to the invention is useful in the treatment of cancer or AIDS, and in gene therapy. |
| 申请公布号 |
WO9411027(A1) |
申请公布日期 |
1994.05.26 |
| 申请号 |
WO1993US11060 |
申请日期 |
1993.11.15 |
| 申请人 |
BOARD OF REGENTS OF UNIVERSITY OF WASHINGTON;PAPAYANNOPOULOU, THALIA |
发明人 |
PAPAYANNOPOULOU, THALIA |
| 分类号 |
A61K45/00;A61K31/505;A61K31/513;A61K35/14;A61K35/28;A61K38/00;A61K38/19;A61K39/395;A61K48/00;A61P7/00;A61P31/18;A61P35/00;A61P37/00;A61P37/04;A61P43/00;C07K16/18;C07K16/28;(IPC1-7):A61K39/395;A61K37/02 |
主分类号 |
A61K45/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
