Diagnosis and treatment of osteoarthritis involving a 92 kd gelatinase

摘要

A 92 kD gelatinase is uniquely found in the chondrocytes or synovial fluid of subjects suffering from degenerative diseases of the cartilage. It is believed that the gelatinase has an active role in the etiology of the disease. Therefore, detection of the presence or absence of the 92 kD gelatinase may be used for diagnosis and treatment with compounds or protocols which inhibit its function or production are useful in therapy.