发明名称 |
Thrombin activatable plasminogen derivatives |
摘要 |
A plasminogen analogue activatable by thrombin to have plasmin activity which contains the cleavage site sequence P4-P3-Pro-Arg-P1'-P2' where P3 is a basic amino acid residue, P4 is a hydrophobic amino acid residue and each of P1' and P2' is independently a non-acidic amino acid residue, said site being cleavable by thrombin between Arg and P1'. |
申请公布号 |
AU5343294(A) |
申请公布日期 |
1994.05.24 |
申请号 |
AU19940053432 |
申请日期 |
1993.10.28 |
申请人 |
BRITISH BIO-TECHNOLOGY LIMITED |
发明人 |
RICHARD JAMES GILBERT;MICHAEL GEORGE HUNTER;KEITH MARTYN DAWSON |
分类号 |
C12N15/09;A61K38/00;A61K38/48;A61P7/02;C07H21/04;C07K7/06;C07K7/08;C07K14/47;C12N9/68;C12N15/57 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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