发明名称 |
Stereoselective reduction of ketones |
摘要 |
The present invention concerns a process for the stereoselective enzymatic reduction of keto group-containing compounds such as N-(4-(2-chloroacetyl)phenyl)methanesulfonamido to form the corresponding hydroxyl-group containing compound. The process is selective for the D(+) enantiomer and is catalyzed by enzymes such as oxido-reductase or dehydrogense, or by microorganisms such as Hansenula, Rhodococcus, or Norcardia species. |
申请公布号 |
AU5044393(A) |
申请公布日期 |
1994.05.19 |
申请号 |
AU19930050443 |
申请日期 |
1993.11.04 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
RAMESH N. PATEL;LASZLO J. SZARKA;AMIT BANERJEE;CLYDE G. MCNAMEE |
分类号 |
A61K31/18;A61P9/00;C07C311/08;C07C311/21;C12P13/02;C12P41/00;C12R1/01;C12R1/645 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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