| 摘要 |
PURPOSE:To obtain the subject granules insoluble in the mouth and stomach but soluble in the intestinal tract, thus excellent in lactobacterial proliferation and contamination resistance by coating lactobacillis and coffee leaves or extract thereof with specific two kinds of layers. CONSTITUTION:The objective granules can be obtained by coating lactobacillis such as Lactobacillus casei or Leuconostoc dextranicum (viable cell number: >=10<6>) and coffee leaves or extract thereof with (A) a layer containing fatty oil (e.g. palm oil, coconut oil) and vehicle (potato starch, egg, glucose) and (B) a layer containing hydrous alcohol-soluble protein (pref. zein, a glyceral fatty acid ester is used as plasticizer). |
