2,2-DIMETHYLCHROMENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS IN WHICH THEY ARE PRESENT

摘要

IN THE C A N A D I A N PATENT /A TRADEMARK OFFICE PATENT APPLICATION entitled: 2,2-Dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present in the names of: Georges GARCIA Alain DI MALTA Patrick GAUTIER Assignee: SANOFI The present invention relates to 2,2-dimethyl-chromene derivatives of the formula : (I) <IMG> in which Z represents a halogen atom or a cyano, nitro, acetyl, phosphono or dialkoxyphosphoryl group, the alkoxy group containing 1 to 3 carbon atoms, and the pharmaceutically acceptable salts of the phosphono group. These compounds show an antihypertensive and antiarrythmic activity. The present invention also relates to a process for the preparation of said compounds and to the pharmaceutical compositions in which they are present.