发明名称 |
PHARMACEUTICALS, PHOSPHORUS-CONTAINING 2-ISOXAZOLINES AND ISOXAZOLES CONTAINED THEREIN, AND PROCESSES FOR THE PREPARATION OF THESE HETEROCYCLIC COMPOUNDS |
摘要 |
Pharmaceuticals, phosphorus-containing 2-isoxazolines and isoxazoles contained therein, and processes for the preparation of these heterocyclic compounds Pharmaceuticals containing or composed of at least one compound of the formula I and/or one of its physiologically tolerated salts where appropriate, where the compounds of the formula I can, where appropriate, be in the form of pure stereoisomers or mixtures thereof; formula I is: <IMG> (I) in which R1 = organic radical or halogen, A = C,C single or C,C double bond, n = 0, 1 or 2, and X and Y = alkyl radical or = -OR2 or -NR2R3 with R2 and R3 = H or optionally substituted aliphatic radical. The pharmaceuticals are suitable for the prophylaxis and/or treatment of diseases of the immune system, especially of tumors, infections and/or autoimmune diseases of the human or animal body and for use as adjuvants for vaccines. Some of the compounds of the formula I are new; the compounds can be prepared by special processes.
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申请公布号 |
CA1329604(C) |
申请公布日期 |
1994.05.17 |
申请号 |
CA19880581138 |
申请日期 |
1988.10.25 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
SCHWAB, WILFRIED;BARTLETT, ROBERT R.;GEBERT, ULRICH;SCHORLEMMER, HANS U.;DICKNEITE, GERHARD;SEDLACEK, HANS H. |
分类号 |
A61K31/675;A61K39/39;A61P35/00;A61P37/00;C07F9/40;C07F9/653;C07F9/6574;(IPC1-7):C07F9/547 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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地址 |
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