METHOD FOR INTRODUCING BIOSUBSTANCE TO CELL USING MAGNETIC FINE PARTICLE AND SELECTIVE CONCENTRATION AND SEPARATION OF CELL BY MAGNETISM

摘要

PURPOSE:To enable magnetic concentration and separation of a cell containing a biosubstance such as gene introduced into the cell by shooting fine magnetic particles supporting immobilized biosubstance into a cell at a high speed. CONSTITUTION:A biosubstance is immobilized on fine magnetic particles and the particles are shot into a cell at a high speed. The cell containing the introduced fine magnetic particles can be selectively and specifically concentrated or separated by a magnetic means. The method is useful for the screening of a drug resistant cell, etc.