发明名称 |
Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
摘要 |
Described is a device for the controlled release and delivery to mammalian tissue of a pharmacologically active agent comprising: (i) an impermeable backing member; (ii) a control membrane lamina consisting essentially of a first polymeric composition of matter which consists essentially of at least one C2-C4 lower olefin-C1-C8 alkyl acrylate and/or methacrylate copolymer having 2-90% by weight of alkyl acrylate and/or methacrylate monomeric units, taken alone, or taken further together with in intimate admixture, a second polymeric composition consisting essentially of a C2-C4 polyalkylene corresponding to the C2-C4 lower alkylene of said copolymer, said second polymeric composition being compatible with said first polymeric composition of matter; and (iii) a pharmacologically active agent reservoir maintained there between comprising said pharmacologically active agent and a carrier therefor and, optionally, one or more excipients and/or enhancers; and (iv) means for maintaining said device in pharmacologically active agent transmitting relationship to the mammalian tissue to be treated.
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申请公布号 |
US5310559(A) |
申请公布日期 |
1994.05.10 |
申请号 |
US19920964478 |
申请日期 |
1992.10.21 |
申请人 |
HERCON LABORATORIES CORPORATION |
发明人 |
SHAH, KISHORE;KYDONIEUS, AGIS |
分类号 |
A61K9/70;A61K31/21;A61M31/00;(IPC1-7):A61F13/00 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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