发明名称 Compositions of iodoaniline derivatives for visualization of the gastrointestinal tract
摘要 Disclosed are contrast agents of the formula <IMAGE> contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z=H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R1 and R2 are independently H, C1-C25 alkyl, cycloalkyl, acetyl or halo-lower-alkyl, wherein said C1-C25 alkyl, cycloalkyl, acetyl and halo-lower-alkyl are optionally substituted with fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, n is 1-4; y is 1-4; and x is 1 or 2.
申请公布号 US5310537(A) 申请公布日期 1994.05.10
申请号 US19930024555 申请日期 1993.03.01
申请人 STERLING WINTHROP INC. 发明人 ILLIG, CARL R.;CAULFIELD, THOMAS J.
分类号 A61K49/04;C07C211/52;C07C225/22;C07C229/18;C07C229/28;C07C233/15;(IPC1-7):C07C211/45;G01N21/00 主分类号 A61K49/04
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