发明名称 |
Cholesterol lowering compounds |
摘要 |
New Zaragozic acids have been isolated from a culture of MF5465. These compounds and their derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia.
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申请公布号 |
US5310949(A) |
申请公布日期 |
1994.05.10 |
申请号 |
US19920939258 |
申请日期 |
1992.09.02 |
申请人 |
MERCK & CO., INC. |
发明人 |
DUFRESNE, CLAUDE;MASUREKAR, PRAKASH S.;FERRELL, LESLIE A.;ZINK, DEBORAH L.;SOSA, MARGARET S. |
分类号 |
C07D493/08;(IPC1-7):C07D319/04 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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