发明名称 |
Cholesterol lowering compounds |
摘要 |
Zaragozic acids isolated from a culture of MF5465 have been subjected to photoreaction, then derivatized at the 4-keto position. The resulting derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia. |
申请公布号 |
AU5361494(A) |
申请公布日期 |
1994.05.09 |
申请号 |
AU19940053614 |
申请日期 |
1993.10.18 |
申请人 |
MERCK & CO., INC. |
发明人 |
LASZLO R. TREIBER;GEORGE A. DOSS;BYRON H. ARISON |
分类号 |
C07D493/08;C07D495/20;C07D498/18 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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