发明名称 |
PROCESS FOR PRODUCTION OF 5-AMINO-3-METHYLPYRAZOLE |
摘要 |
The process for producing 5-amino-3-methyl-pyrazole includes the steps of reacting 2,3-dichloro-propene with a cyanogenating agent in the presence of a cuprous salt and water at a pH of 3-8 to obtain at least one intermediate selected from the group consisting of 3-chloro-3-butenonitrile and 2,3-butadienenitrile; reacting the at least one intermediate with a base in the presence of water at a pH of 12.5 or above to obtain 2-butynenitrile; and reacting the 2-butynenitrile with hydrazine. This process is advantageous in that it enables the production of 5-amino-3-methylpyrazole in high yield without using any reagent which may produce fire. 5-Amino-3-methylpyrazole is a useful intermediate for medicines, agricultural chemicals, photographic chemicals, etc.
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申请公布号 |
CA2107944(A1) |
申请公布日期 |
1994.05.06 |
申请号 |
CA19932107944 |
申请日期 |
1993.10.07 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
MINAMISAKA, KAZUYA;SEKIGUCHI, MASAHITO;SAITO, KENJI |
分类号 |
C07C253/14;C07D231/38;(IPC1-7):C07C255/07;C07C253/30 |
主分类号 |
C07C253/14 |
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