发明名称 |
VERFAHREN ZUM AUFSPÜREN, IDENTIFIZIEREN UND QUANTIFIZIEREN VON ORGANISMEN UND VIREN. |
摘要 |
<p>A probe for the quantitative or qualitative determination of one or more rRNA or tRNA-containing procaryotic or eucaryotic target organism(s) infecting a human or animal body, or for determining a genetic condition occurring in a human or animal body is described, said probe comprising a labelled oligonucleotide complementary to a unique rRNA or tRNA sequence of a target organism or a group or target organisms that is to be determined, and not hybridizing significantly with the non-target organism(s), said probe having been prepared by (i) selecting a target organism or a group of target organisms, and (ii) preparing a labelled oligonucleotide which is complementary to a unique RNA sequence of said target organism(s) by hybridization screening and/or selection from a known RNA sequence, and (iii) verifying that the oligonucleotide does not significantly hybridize to non-target organisms. w</p> |
申请公布号 |
DE3486254(T2) |
申请公布日期 |
1994.05.05 |
申请号 |
DE19843486254T |
申请日期 |
1984.01.09 |
申请人 |
GEN-PROBE INC., SAN DIEGO, CALIF., US |
发明人 |
KOHNE, DAVID, E., LA JOLLA, CA 92037, US |
分类号 |
A61K35/00;A61K38/00;C07H1/00;C07H21/02;C07H21/04;C12N1/06;C12N15/00;C12N15/02;C12N15/09;C12P19/34;C12Q1/04;C12Q1/06;C12Q1/18;C12Q1/68;C12Q1/70;G01N33/50;G01N33/53;G01N33/566;G01N33/569;G01N33/58;(IPC1-7):C12Q1/68 |
主分类号 |
A61K35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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