发明名称 |
Method to directly radiolabel antibodies for diagnostic imaging and therapy |
摘要 |
The invention is a novel method and kit for directly radiolabeling proteins such as antibodies or antibody fragments for diagnostic and therapeutic purposes. The method comprises incubating a protein-containing solution with a solution of sodium ascorbate; adding a required quantity of reduced radionuclide to the incubated protein. A kit is also provided wherein the protein and/or reducing agents may be in lyophilized form.
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申请公布号 |
US5308603(A) |
申请公布日期 |
1994.05.03 |
申请号 |
US19900591964 |
申请日期 |
1990.10.02 |
申请人 |
THOMAS JEFFERSON UNIVERSITY |
发明人 |
THAKUR, MATHEW L. |
分类号 |
A61K51/10;A61K51/12;(IPC1-7):A61K49/02;A61K43/00 |
主分类号 |
A61K51/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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