| 发明名称 |
Method for production of therapeutically applicable 7- substituted acetamido-3-alkenyl-3-cephem derivative |
| 摘要 |
There is disclosed a process for the production of certain 2-allyl-, and 3-butenyl-3-cephem derivatives by coupling a 3-chloromethyl-3-cephem with a hydrocarbyltributystannane in the presence of bis(dibenzylideneacetonyl)-palladium and a phosphine. The 3-allyl- and 3-butenyl-3-cephem derivatives so-produced are useful as broad-spectrum antibacterial agents. |
| 申请公布号 |
FI91760(B) |
申请公布日期 |
1994.04.29 |
| 申请号 |
FI19880001872 |
申请日期 |
1988.04.21 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BAKER, STEPHEN R.;FARINA, VITTORIO;SAPINO, JR., CHESTER |
| 分类号 |
C07D501/18;A61K31/545;A61K31/546;A61P31/04;B01J27/13;B01J31/04;B01J31/22;C07D;C07D501/00;C07D501/04;C07D501/16;C07D501/20;C07D501/22;C07D501/24;C07D501/38;C07D501/46;C07D501/59;C07F7/10;(IPC1-7):C07D501/04 |
主分类号 |
C07D501/18 |
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