| 摘要 |
<p>A novel asymmetric synthesis is provided for preparing optically active amides of formula (A) and their salts. In the formula, X represents (a) or (b), R represents a mono or bicyclic aryl or heteroaryl group, R is an aryl or heteroaryl radical and R?2 and R3¿ have specified meanings. The products are useful as 5-HT¿1A? antagonists. Novel diesters useful as intermediates in the process are also disclosed.</p> |
