Prepn. of N-alkanoyl poly:hydroxy:alkylamine deriv. of saccharide - from poly:hydroxy:alkylamine and alkyl ester of carboxylic acid by adding amine soln., removing water, adding basic catalyst for reacting with removal of alcohol by distn.

摘要

Prepn. of N-alkanoyl-polyhydroxyalkylamines of formula Z-N(R1)C(=O)R2 (I) comprises reacting polyhydroxyalkylamines of formula Z-NH-R1 (II) with alkyl esters of carboxylic acids of formula R3-O-C(=O)-R2 (III), in presence of a basic catalyst. In the prepn. of (a) the total amt. of (III) is heated to 90-130 deg.C and an aq. soln. of (II) is added, with the water introduced being continuously removed by distn. (b) the catalyst is added to the fine suspension of (II) in (III) and conversion to (I) is carried out at 70-100 deg.C with continuous removal by distn. of the alcohol, R3-OH formed and (c) conversion is in absence of organic solvents. In the formulae, Z = polyhydroxyalkyl residue of a mono- or oligo-saccharide; R1 = H or 1-8C alkyl; R2 = 1-21C alkyl; R3 = 1-4C alkyl. USE/ADVANTAGE - (I) are surfactants, used in washing and cleaning compsns. Colourless or light coloured prods. with a high (I) content and smaller amts. of starting materials and by-prods. are obtd. needing no further purification. Formation of clumps and deposits in the reactor is avoided, and the process can be used on the large scale.