| 发明名称 |
MODIFIED CILIARY NEUROTROPHIC FACTORS |
| 摘要 |
Human ciliary neurotrophic factor is modified by amino acid substitution to give CNTF's of value in treating diseases or disorders of the nervous system. Recombinant DNA techniques for their production are described. Also described is a method of screening for novel therapeutic proteins by determining altered electrophoretic binding properties. |
| 申请公布号 |
WO9409134(A2) |
申请公布日期 |
1994.04.28 |
| 申请号 |
WO1993US09649 |
申请日期 |
1993.10.08 |
| 申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
PANAYOTATOS, NIKOS |
| 分类号 |
A61K38/00;A61P21/00;A61P25/00;A61P25/28;B01D57/02;C07K14/47;C07K14/475;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12N15/18;C12P21/02;C12R1/19;G01N27/447;G01N33/68 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
