发明名称 AZOLE COMPOUND
摘要 A compound represented by general formula (I), wherein R<1> represents imidazolyl, triazolyl or tetrazolyl each of which may be substituted by methyl and/or ethyl. R<2> represents naphthyl, phenanthryl or anthryl each of which may be substituted by substituent(s) selected from the following group A: C1-C4 alkyl, C1-C4 alkoxy, C1-C6 acyloxy, aromatic acyloxy, OH, trialkyl, C1-C4 acyl amino, alkoxyalkoxy, alkoxyacyloxy and trialkylsilyloxy; and R<3> represents hydrogen, methyl or cyano. This compound has an excellent aromatase inhibitor activity and is useful particularly as a remedy for breast cancer.
申请公布号 WO9408973(A1) 申请公布日期 1994.04.28
申请号 WO1993JP01509 申请日期 1993.10.20
申请人 SANKYO COMPANY, LIMITED 发明人 SHIBATA, TOMOYUKI;SUGIMURA, YUKIO;TANZAWA, KAZUHIKO;TAKAHASHI, MASAAKI;KOBAYASHI, TOMOWO;MITSUHASHI, YOSHIHIRO
分类号 C07D233/54;C07D233/61;C07D233/64;C07D257/04;C07D521/00;(IPC1-7):C07D233/61;A61K31/415;A61K31/41;C07D249/02 主分类号 C07D233/54
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