发明名称 NOVEL AMINO ACID DERIVATIVES
摘要 A novel amino acid derivative represented by the general formula (I) shown below or a salt thereof have now been provided by chemical synthesis, and it has been found that these new compounds stimulate proliferation and physiological activities of the T cells of mammals, have an immunomodulating activity and also have an antitumor activity or a carcinostatic activity. It has also been found that these new compounds have an effect of stimulating the proliferation of hematopoietic stem cells. <IMG> (I) wherein y is O or 1; R1 represents an unsubstituted C1-C8 alkyl group or others; R2 represents a hydrogen atom, a C1-C5 alkyl group or others; R3 represents a hydrogen atom, a C1-C8 alkyl group or others; R4 represents a hydrogen atom, a C1-C3 alkyl group or others; R5 represents a group -OR42, a group <IMG> or others.
申请公布号 CA2125679(A1) 申请公布日期 1994.04.28
申请号 CA19932125679 申请日期 1993.10.15
申请人 ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI;KANEGAFUCHI KAGAKU KOGYO KABUSHYIKI KAISHA 发明人 MASAAKI ISHIZUKA;KAWAZU, MASAJI;KATSUMI, TOSHIAKI;FUSE, YOSHIHIDE;MAEDA, KENJI;TAKEUCHI, TOMIO;ISHIZUKA MASAAKI
分类号 C07C233/47;C07C235/12;C07C237/12;C07C323/59;C07D233/88;(IPC1-7):C07C235/12;A61K38/05;C07K5/06;C07D209/18;A61K31/195;A61K31/215;C07D233/26;C07D277/30;A61K31/405;C07C323/41;A61K31/41 主分类号 C07C233/47
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