| 发明名称 |
O-ALKYLATED RAPAMYCIN DERIVATIVES AND THEIR USE, PARTICULARLY AS IMMUNOSUPPRESSANTS |
| 摘要 |
The present invention is directed to novel 0-alkylated derivatives of rapamycin of formula (I), especially 40-0-alkylated derivatives, are found t o have pharmaceutical utility, particularly as an immunosuppressants. |
| 申请公布号 |
CA2476257(A1) |
申请公布日期 |
1994.04.28 |
| 申请号 |
CA19932476257 |
申请日期 |
1993.09.24 |
| 申请人 |
NOVARTIS AG |
发明人 |
COTTENS, SYLVAIN;SEDRANI, RICHARD |
| 分类号 |
A61K31/00;A61K31/435;A61K31/4353;A61K31/436;A61K31/455;A61K31/496;A61K31/52;A61K31/5377;A61K31/573;A61K38/00;A61K39/395;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P31/04;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P43/00;C07D498/18;C07F7/18;(IPC1-7):C07D498/18 |
主分类号 |
A61K31/00 |
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