Arylmethylphosphonates and phosphonic acids useful as anti-inflammatory agents

摘要

This invention provides a new use of acids, esters, and salts of arylmethylphosphonates of Formula I, or phosphonic acid derivatives of Formula II as anti-inflammatory and anti-arthritic agents. Representative compounds include 4-dodecyloxybenzylphosphonic acid dimethyl ester, (2-naphthalenylmethyl)phosphonic acid dimethyl ester, and ([1,1 '-biphenyl]-2-ylmethyl)phosphonic acid dimethyl ester. The invention also provides novel acids, esters, and salts of arylmethylphosphonic acid, phosphonic acid and derivatives.