发明名称 Botulinum toxin neutralizer
摘要 A botulinum toxin neutralizer comprising at least one fatty acid having the number of carbon atoms of at least 12. Such a fatty acid may be any of saturated fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, nonadecanoic acid, arachidic acid, and behenic acid or any of unsaturated fatty acids such as oleic acid. The toxin neutralizer acts as if it were an antagonistic receptor for botulinum toxin and, when encountering botulinum toxin in human body, directly combines with the toxin and disables the toxin from combining with the neuromuscular tissues of human body to prevent the outbreak of botulism. The toxin thus neutralized and affixed to the botulinum toxin neutralizer is excreted from the human body. The botulinum toxin neutralizer can be manufactured easily and economically from a naturally occurring glyceride and is thus far less costly then the known antitoxin of ganglioside GT1b produced from bovine brain.
申请公布号 US5306730(A) 申请公布日期 1994.04.26
申请号 US19920887652 申请日期 1992.05.26
申请人 KABUSHIKI KAISHA YAKULT HONSHA 发明人 NAGAI, YOSHITAKA;TAKAMIZAWA, KOUTARO;TANAKA, RYUICHIRO;TAKAYAMA, HIROO;SAKURAI, TOSHIZO;MUTAI, MASAHIKO
分类号 A61K31/20;(IPC1-7):A61K31/20 主分类号 A61K31/20
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