发明名称 Preparation process for arylacetic acids and their alkali metal salts
摘要 Process for obtaining an arylacetic acid of general formula (I): Ar-CHR-COOH (I) in which R=H, C1-C4 alk, Ar=2-thienyl, 3-thienyl, 1-naphthyl, 2-naphthyl, 1-(2-methoxy naphthyl), 3,4-methylenedioxy phenyl or phenyl of general formula (II): (* CHEMICAL STRUCTURE *) (II) in which R1=H, OH or C1-C4 alkoxy, R2=H, C1-C4 alk, C1-C4 alkoxy or OH, as well as their alkali metal salts, by reaction in a solvent of the corresponding arylglycolic acid of general formula (III): Ar-CR(OH)-COOH (III) or one of its alkali metal salts with a hydrogen donor agent chosen from the group constituted by: formic acid, or one of its alkali metal salts, phosphonic acid, phosphinic acid, or one of their alkali metal salts, in the presence of a hydrogen transfer catalyst, which if desired is isolated or salified, and use for the preparation of certain acids of formula (I).
申请公布号 US5306833(A) 申请公布日期 1994.04.26
申请号 US19930012632 申请日期 1993.02.03
申请人 SOCIETE FRANCAISE HOECHST 发明人 VALLEJOS, JEAN-CLAUDE;CHRISTIDIS, YANI
分类号 C07D317/60;C07C51/377;C07C57/32;C07C57/40;C07C59/52;C07C59/64;C07D333/24;(IPC1-7):C07C51/377;C07C67/297 主分类号 C07D317/60
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