| 摘要 |
Novel derivatives of taxol analogues of general formula (I) preparation thereof and compositions containing them. In general formula (I): Ar stands for an aryl radical, R is a phenyl radical or a radical of general formula R6-O- (R6 = alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, optionally substituted bicycloalkyl), phenyl or heterocyclyl, R1 is an alkyl radical, cycloalkyl, aryl, heterocyclyl, cycloalkylalkyl, aralkyl or heterocyclylalkyl substituted by hydroxy, carboxy, alkyloxycarbonyl or (III). The novel products of general formula (I) have remarkable antitumor and antileukemia properties. |
