发明名称 |
Förfaranden för in vivo bestämning av koncentrationen av NMR-detekterbara xenobiotiska föreningar |
摘要 |
Methods wherein the concentration of NMR-detectable xenobiotic compounds may be determined in living subjects by in vivo measurement of one or more magnetic resonance signals. In preferred embodiments, the present invention provides a method for evaluating, in vivo, the clearance rate of a xenobiotic compound from a living subject, thereby providing a noninvasive method for determining the status of the excretory organs of the subject, and a method for determining the proper dosing regimen of a pharmacologically active compound to be administered to the subject. |
申请公布号 |
FI941832(A0) |
申请公布日期 |
1994.04.20 |
申请号 |
FI19940001832 |
申请日期 |
1994.04.20 |
申请人 |
BRISTOL-MEYRS SQUIBB COMPANY |
发明人 |
TWEEDLE, MICHAEL F.;STRAUSS, HARRY WILLIAM;NUNN, ADRIAN D. |
分类号 |
A61B5/055;A61K49/00;A61K49/06;G01N24/08;G01R33/28;G01R33/465;(IPC1-7):A61B |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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