| 发明名称 |
METHOD AND COMPOSITIONS FOR SOLUBILIZATION AND STABILIZATION OF POLYPEPTIDES, ESPECIALLY PROTEINS |
| 摘要 |
The invention provides a method for the solubilization and/or stabilization of polypeptides, especially proteins, by means of cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl ant maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin. Solubilized ant/or stabilized compositions comprising a polypeptide, especially a protein, and the selected cyclodextrin are also described.
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| 申请公布号 |
CA1328634(C) |
申请公布日期 |
1994.04.19 |
| 申请号 |
CA19890612516 |
申请日期 |
1989.09.22 |
| 申请人 |
CETUS CORPORATION |
发明人 |
HORA, MANINDER S.;RUBINFELD, JOSEPH;STERN, WARREN;WONG, GREGORY J. |
| 分类号 |
A61K9/08;A61K9/18;A61K38/00;A61K38/21;A61K38/22;A61K38/28;A61K38/44;A61K38/46;A61K47/40;A61K47/48;(IPC1-7):C12N9/96 |
主分类号 |
A61K9/08 |
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