摘要 |
<p>Methods to enrich for human hematopoietic stem cells by selection for cells which express c-kit protein are provided. A human stem cell gives rise to progeny in all defined hematopoietic lineages, and is capable of fully reconstituting an immunocompromised host in all blood cell types, including the pluripotent human stem cell with limiting numbers of cells. C-kit is expressed by a number of early hematopoietic progenitors, including the human stem cell. Selection for cells which express c-kit provides a method to enrich for human hematopoietic stem cells.</p> |