发明名称 Phospholipase A¶2¶ inhibierende Phosphatidylcholinverbindungen
摘要 The invention concerns compounds of the general formula (I), in which R<1> is a C10-C22 alkyl group, R<2> is an O-CO-R<4>, NH-CO-R<4>, -OH, -OCH3, -OC2H5, -OC3H7, -NH2, -NHCH3, -N(CH3)2 or -N<+>(CH3)3Cl<-> group, R<4> is a C1-C20 alkyl group and R<3> is one of the following groups: -C2H4-N<+>(CH3)3, -C2H4-N<+>H(CH3)2, -C2H4-N<+>H2CH3, -C2H4-N<+>H3, pentahydroxycyclohexanyl derivatives, in particular myo-inositol derivatives, 1,2- or 2,3-(R or S)-dihydroxypropanyl, seryl (D or L), N-methylseryl (D or L), N,N-dimethylseryl, (D or L), N,N,N-trimethylseryl (D or L), H, methyl, ethyl, hydroxyethyl, 3-hydroxypropyl, 2-hydroxypropyl, R<2> and (II) being interchangeable with each other, plus enantiomers thereof.
申请公布号 DE4234130(A1) 申请公布日期 1994.04.14
申请号 DE19924234130 申请日期 1992.10.09
申请人 MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN EV, 37073 GOETTINGEN, DE 发明人 EIBL, HANSJOERG, PROF. DR., 37120 BOVENDEN-EDDIGEHAUSEN, DE;MASSING, ULRICH, DR., 37073 GOETTINGEN, DE;UNGER, CLEMENS, PROF. DR., 37085 GOETTINGEN, DE
分类号 A61K31/66;A61P7/02;A61P29/00;A61P43/00;C07F9/09;C07F9/117;(IPC1-7):C07F9/10;A61K31/685;C12N9/99;C12N9/16 主分类号 A61K31/66
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