发明名称 BOVINE PANCREATIC TRYPSIN INHIBITOR DERIVED INHIBITORS OF FACTOR VIIA - TISSUE FACTOR COMPLEX
摘要 Compounds derived from BPTI which inhibit factor VIIa-TF complex with an inhibition constant of less than 500 nM, their pharmaceutical compositions, and methods of use. Also disclosed are isolated nucleic acid segments encoding for the compounds, vectors comprising the nucleic acid segment and promoter, transformed host cells, and a method for preparing the compounds using transformed host cells.
申请公布号 CA2145517(A1) 申请公布日期 1994.04.14
申请号 CA19932145517 申请日期 1993.07.01
申请人 CORVAS INT INC 发明人 LASTERS IGNACE;DE MAEYER MARC;RIPKA WILLIAM C
分类号 C12N15/09;A61K38/00;A61K38/55;A61P7/02;C07K14/81;C12N1/19;C12N1/21;C12N15/15;C12P21/02;C12R1/19;C12R1/84;(IPC1-7):C12N15/15;A61K38/57;C12N15/70;C12N15/81 主分类号 C12N15/09
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