| 发明名称 |
METHOD FOR ANTAGONIZING INOSITOL 1,4,5-TRIPHOSPHATE |
| 摘要 |
Oligomers of formula (I) have been demonstrated to be effective antagonists of inositol 1,4,5-triphosphate (IP3) by competitively vying with IP3 for binding sites. By competitively inhibiting the activity of IP3, the oligomers of this invention can modulate the release of intracellular calcium and elicit the resultant physiological effects. |
| 申请公布号 |
WO9407507(A1) |
申请公布日期 |
1994.04.14 |
| 申请号 |
WO1993US08168 |
申请日期 |
1993.08.30 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
STAUDERMAN, KENNETH, A. |
| 分类号 |
A61K31/785;A61K31/17;A61K31/795;A61P43/00;C07C309/51;C08G71/02 |
主分类号 |
A61K31/785 |
| 代理机构 |
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