| 摘要 |
<p>A vaccine, useful for fertility control and cancer treatment, comprises an antigenic conjugate of a protein reproductive hormone, a fragment of such a hormone, or a peptide substantially immunologically equivalent to such a hormone or fragment conjugated with a chemically-modified diphtheria toxoid, and an adjuvant, both dispersed in an aqueous medium and emulsified with a mixture of oils. An antigenic conjugate which can be used in this or a similar vaccine, comprises a protein reproductive hormone, a fragment of such a hormone, or a peptide substantially immunologically equivalent to such a hormone or fragment, coupled to an epitope peptide having the sequence of at least one T cell lymphocyte epitope of a protein foreign to the animal to be treated with the conjugate, or a sequence substantially immunologically equivalent to such an epitope.</p> |
