| 摘要 |
<p>A buffered intravesicular pharmaceutical dosage system for delivery of TGFαPE40ab to a human bladder for bladder cancer chemotherapy, in which a buffer system of 100 mM phosphate at an initial pH of 7.8 maintains a pH range in the bladder of 6.5 to 7.8 that is sufficient to maximize interaction of TGFαPE40ab with the EGF receptor expressed on the surface of bladder cancer cells and to prevent aggregation of the TGFαPE40ab while in the bladder.</p> |
