发明名称 ANTI-INFLAMMATORY, TOLEROGENIC AND IMMUNOINHIBITING PROPERTIES OF CARBOHYDRATE BINDING PEPTIDES
摘要 The present invention is directed to methods of supressing inflammatory responses, inducing tolerance to an antigen, and suppressing cell adhesion, e.g., involved in metastasis, by the administration of lectin derived carbohydrate binding peptides or derivatives thereof, in particular, peptides capable of binding terminally linked .alpha.-sialic acid(2~6).beta.Gal-and/or .alpha.-sialic acid(2~3).beta.Gal-groups on structures or molecules comprising such groups. Pharmaceutical compositions containing such lectin derived carbohydrate binding peptides or derivatives thereof are also disclosed.
申请公布号 CA2282888(A1) 申请公布日期 1994.04.14
申请号 CA19932282888 申请日期 1993.10.04
申请人 ALBERTA RESEARCH COUNCIL 发明人 ARMSTRONG, GLEN D.;SMITH, RICHARD;HEERZE, LOUIS D.
分类号 A61K38/08;A61K39/35;C07K7/06;(IPC1-7):C07K7/06 主分类号 A61K38/08
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