发明名称 |
MICROORGANISMS FOR THE PRODUCTION OF TRYPTOPHAN AND PROCESS FOR PRODUCING THE SAME |
摘要 |
Microorganisms for the production of tryptophan and a process for producing the same are disclosed. These microorganisms are characterised by a deregulated tryptophan metabolism and by a feedback-resistant serA-allele deregulated serine metabolism. When the disclosed strains were fermented, it has been surprisingly shown that the strains with the highest tryptophan yield are those which contain a feedback-resistant serA-allele with a Ki value for serine from 100 .mu.M to 50 mM and a deregulated tryptophan metabolism having a trpE-allele with a Ki value for tryptophan from 0.1 mM to 20 mM.
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申请公布号 |
CA2145630(A1) |
申请公布日期 |
1994.04.14 |
申请号 |
CA19932145630 |
申请日期 |
1993.09.23 |
申请人 |
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发明人 |
WICH, GUENTER;LEINFELDER, WALFRED;BACKMAN, KEITH |
分类号 |
C12N15/09;C12N1/20;C12N1/21;C12N15/01;C12N15/52;C12P13/22;C12R1/15;C12R1/19;(IPC1-7):C12P13/22;C12N15/53 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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