发明名称 |
Polymer-based drug delivery system |
摘要 |
Described herein is a drug delivery system useful to deliver drugs at low dosage levels to patients in a sustained fashion and at a controlled rate. The system comprises a wettable polymeric matrix in which is dispersed a multiplicity of particles containing a substantially homogeneous blend of osmotically active excipient and not more than about 10% by weight of drug. The system is particularly well suited for delivery of therapeutic macromolecules such as protein drugs. Delivery of epidermal growth factor is exemplified.
|
申请公布号 |
US5302397(A) |
申请公布日期 |
1994.04.12 |
申请号 |
US19910793836 |
申请日期 |
1991.11.19 |
申请人 |
AMSDEN, BRIAN G.;CHENG, YU-LING |
发明人 |
AMSDEN, BRIAN G.;CHENG, YU-LING |
分类号 |
A61K9/00;A61K9/20;A61K9/22;A61K9/26;A61K38/18;A61K38/47;(IPC1-7):A61K9/26 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|