发明名称 |
Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use |
摘要 |
Compounds of formula (I): <IMAGE> (I) (in which: R1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R2 is an aryl-substituted alkyl group, a heterocyclic-substituted alkyl group or a diarylamino group; R3 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or an alkenyl group having from 3 to 6 carbon atoms; and each of the bonds represented by alpha - beta and gamma - delta is a carbon-carbon single bond or a carbon-carbon double bond;) and pharmaceutically acceptable salts and esters thereof are useful for the treatment and prophylaxis of prostatic hypertrophy. We also provide processes for their preparation.
|
申请公布号 |
US5302621(A) |
申请公布日期 |
1994.04.12 |
申请号 |
US19930023871 |
申请日期 |
1993.02.26 |
申请人 |
SANKYO COMPANY, LIMITED |
发明人 |
KOJIMA, KOICHI;KURATA, HITOSHI;HORIKOSHI, HIROYOSHI;HAMADA, TAKAKAZU |
分类号 |
A61K31/56;A61K31/58;A61P13/02;A61P15/00;A61P43/00;C07J73/00;(IPC1-7):A61K31/58 |
主分类号 |
A61K31/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|