发明名称 1,1-DIOXO-CEPHEM-4-CARBOTHIOLSÄURE-DERIVATE.
摘要 There are provided compounds I <IMAGE> I wherein A is a hydrogen atom or an organic group, R1 is hydrogen or halogen atom or an organic group, R2 is hydrogen or halogen atom, C1-C4 alkyl or acyloxy group, R3 is hydrogen atom, C1-C4 alkyl or alkoxy, benzyl group or a methylene and R4 is chloro, fluoro, hydrogen atom or an organic group. The compounds I are elastase inhibitors. A process for their preparation is also provided, as are pharmaceutical compositions containing them.
申请公布号 DE68913498(D1) 申请公布日期 1994.04.07
申请号 DE1989613498 申请日期 1989.05.08
申请人 FARMITALIA CARLO ERBA S.R.L., MAILAND/MILANO, IT 发明人 ALPEGIANI, MARCO, I-20100 MILAN, IT;BISSOLINO, PIERLUIGI, I-S. GIORGIO DI LOMELLINA, IT;PERRONE, ETTORE, I-20010 BOFFALORA TICINO, IT;DI MATTEO, FRANCESCO, I-20100 MILAN, IT;OREZZI, PIERGIUSEPPE, I-20100 MILAN, IT;CASSINELLI, GIUSEPPE, I-27058 VOGHERA, IT
分类号 C07D519/06;A61K31/545;A61K31/546;A61K38/55;A61P11/00;A61P17/00;A61P19/06;A61P29/00;A61P43/00;C07D501/00;C07D501/20;C07K1/113;C07K5/06;C07K5/08;C07K14/81;(IPC1-7):C07D501/00 主分类号 C07D519/06
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