摘要 |
There are provided compounds I <IMAGE> I wherein A is a hydrogen atom or an organic group, R1 is hydrogen or halogen atom or an organic group, R2 is hydrogen or halogen atom, C1-C4 alkyl or acyloxy group, R3 is hydrogen atom, C1-C4 alkyl or alkoxy, benzyl group or a methylene and R4 is chloro, fluoro, hydrogen atom or an organic group. The compounds I are elastase inhibitors. A process for their preparation is also provided, as are pharmaceutical compositions containing them. |
申请人 |
FARMITALIA CARLO ERBA S.R.L., MAILAND/MILANO, IT |
发明人 |
ALPEGIANI, MARCO, I-20100 MILAN, IT;BISSOLINO, PIERLUIGI, I-S. GIORGIO DI LOMELLINA, IT;PERRONE, ETTORE, I-20010 BOFFALORA TICINO, IT;DI MATTEO, FRANCESCO, I-20100 MILAN, IT;OREZZI, PIERGIUSEPPE, I-20100 MILAN, IT;CASSINELLI, GIUSEPPE, I-27058 VOGHERA, IT |