发明名称 NOVEL 7-(SUBSTITUTED)-8-(SUBSTITUTED)-9-(SUBSTITUTED AMINO)-6- -DEMETHYL-6-DEOXYTETRACYCLINES
摘要 Disclosed are compound of general formula (I), wherein X is C1, R is H, amino, dimethylamino or diethylamino and R1 is H, iodine, amino group, which is eventually substituted by formyl group or carboxyl group, or hydrazine group, and their pharmaceutically suitable salts with organic or anorganic acids. Intermediates of formula (III), wherein Y is -N2+Cl- or azide, X is Cl and R1 is H, and their salts with organic or anorganic salts; method for production of various sections of compounds of formula (I), compounds of formula (I) for use to prevent, treat or reject bacterial infections of warm-blooded animals and pharmaceutical preparations based on them.
申请公布号 SK85793(A3) 申请公布日期 1994.04.06
申请号 SK19930000857 申请日期 1993.08.09
申请人 AMERICAN CYANAMID COMPANY 发明人 SUM PHAIK-ENG;LEE VING J.;HLAVKA JOSEPH J.;TESTA RAYMOND T.
分类号 A61K31/65;A61P31/00;A61P31/04;C07C;C07C237/26;C07C239/18;C07C243/20;C07C245/20;C07C247/18;C07C255/41;C07C271/24;C07C271/60;C07C309/39;C07C309/65;C07C317/28;C07C323/59;C07D205/04;C07D207/16;C07D209/52;C07D221/22;C07D231/14;C07D233/61;C07D233/96;C07D241/12;C07D249/04;C07D249/08;C07D249/10;C07D249/16;C07D257/04;C07D261/08;C07D265/30;C07D265/36;C07D279/12;C07D295/08;C07D295/14;C07D295/20;C07D295/22;C07D307/18;C07D333/06;C07D333/36;C07D453/06;C07D471/08;C07D487/08;(IPC1-7):C07C237/26;C07C35/44 主分类号 A61K31/65
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