发明名称 |
17-Aryl and 17-heterocyclyl-5-beta, 14-beta-andostane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same. |
摘要 |
17-Aryl and 17-heterocyclyl-5 beta ,14 beta -androstane derivatives of general formula (I): <CHEM> wherein: the symbol means that the substituents in position 17 can have an alpha or beta configuration; the symbol --- represents a single or a double bond; Y, R and R<1> have the meanings given in the description; a process for producing same, pharmaceutical compositions containing same as active ingredient, and their use in the preparation of a pharmaceutical agent for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.
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申请公布号 |
EP0590272(A2) |
申请公布日期 |
1994.04.06 |
申请号 |
EP19930112500 |
申请日期 |
1993.08.04 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
ALIMIRANTE, NICOLETTA;BERNARDI, LUIGI;CERRI, ALBERTO;MELLONI, PIERO;PADOANI, GLORIA;QUADRI, LUISA |
分类号 |
A61K31/565;A61K31/575;A61K31/58;A61P9/00;A61P9/12;C07J1/00;C07J9/00;C07J17/00;C07J31/00;C07J33/00;C07J41/00;C07J43/00;C07J51/00;(IPC1-7):C07J9/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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