GROUP B STREPTOCOCCUS TYPE II AND TYPE V POLYSACCHARIDE-PROTEIN CONJUGATE VACCINES
摘要
This invention relates to antigenic conjugate molecules comprising the capsular polysaccharide of Group B streptococcus type II which are covalently linked to protein. This invention further relates to antigenic conjugate molecules comprising the capsular polysaccharide of Group B streptococcus type V which are covalently linked to protein. This invention also relates to vaccines and methods of immunizing mammals, including humans against infection by Group B streptococcus type II (GBS II) and/or Group B streptococcus type V (GBS V). Multivalent vaccines comprising the conjugate molecules of this invention and antigens to other pathogenic bacteria are also claimed.
申请公布号
WO9406467(A1)
申请公布日期
1994.03.31
申请号
WO1993US09056
申请日期
1993.09.24
申请人
BRIGHAM AND WOMEN'S HOSPITAL, INC.;NATIONAL RESEARCH COUNCIL OF CANANDA