<p>A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without inactivation, methods for adapting HAV to growth in MRC-5, vaccine compositions and method of vaccinating humans against HAV infection.</p>
申请公布号
WO9406446(A1)
申请公布日期
1994.03.31
申请号
WO1993US08610
申请日期
1993.09.17
申请人
SMITHKLINE BEECHAM BIOLOGICALS, S.A.;GOVERNMENT OF THE UNITED STATES OF AMERICA, ON BEH
发明人
FUNKHOUSER, ANN, W.;EMERSON, SUZANNE, U.;PURCELL, ROBERT, H.;D'HONDT, ERIC
