Thiazolidone compounds and method of using the same as a vasodilator

摘要

Compounds of formula (I): (* CHEMICAL STRUCTURE *) (I) wherein W represents a sulfur atom and X represents a group of formula -N(R1)-, or W represents a group of formula -N(R1)- and X represents a sulfur atom; R1 is hydrogen, alkyl or aralkyl; R2 and R3 are each hydrogen, alkyl, aralkyl, aryl or aromatic heterocyclic; R4 is hydrogen, alkyl or aralkyl; and A is alkylene which is optionally substituted by carboxy; and pharmaceutically acceptable salts and esters thereof, have a valuable vasodilatory activity.