发明名称 Antiviral pyrimidine nucleosides
摘要 Antiviral nucleosides of formula (I), wherein: Y is hydroxy or amino; X is hydrogen, hydroxy, mercapto, halo, trifluoromethyl, methyl, C2-6alkyl, C1-6haloalkyl, hydroxyC1-3alkyl, formyl, C2-6alkenyl, C2-6haloalkenyl, C2-6alkynyl, C1-6alkoxy, C1-6alkylthio, C1-6alkoxyC1-2alkyl, C1-6alkylthiomethyl, amino, monoC1-6alkylamino, diC1-6alkylamino, cyano, thiocyanate or nitro; R2 is hydrogen and R3 is hydroxy or hydrogen, or together R2 and R3 form a carbon-carbon bond; and physiologically functional derivatives thereof. Compositions containing the compounds, their use in treatment and therapy of viral disease, and processes for the production of the compounds are also provided.
申请公布号 AU4973393(A) 申请公布日期 1994.03.29
申请号 AU19930049733 申请日期 1993.09.03
申请人 UNIV BIRMINGHAM;WELLCOME FOUND 发明人 MILLER JOHN ALLEN;YOUNG ROBERT JOHN;RAHIM SAAD GEORGE;SELWOOD DAVID LAWRENCE;WALKER RICHARD
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61P31/12;C07H19/06 主分类号 A61K31/70
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